International Research and Academic scholar society

IRASS Journal of Applied Medical and Pharmaceutical Sciences

Issue-2(February), Volume-2 2025

1. Review: History of Antihypertension
2

Kanchan V. Mahure*, Mrunali S....
Shri swami samarth Institute of Pharmacy, Dhamangaon parsodi
1-7
https://doi.org/10.5281/zenodo.14890566

Hundreds of thousands that people worldwide suffering about hypertension, becoming an important risk factor for kidney problems, stroke, and cardiovascular disease. In order to prevent such problems along with improving patient outcomes, blood pressure can only be properly managed. The purpose of this review is to provide an extensive examination of the state of antihypertensive treatments and approaches, including prescription drugs, adjustments to lifestyles, and device-based treatments.To find significant studies and recommendations on the medical management of hypertension, an extensive review of the main databases was carried conducted. The biological makeup of hypertension, risk identification, and treatment modalities—including combo and monotherapy—are all discussed in the review

2. Review: History of Antibiotics
5

Snehal kohale*, Mrunali S. Pot...
Shri swami samarth Institute of Pharmacy, Dhamangaon parsodi
8-10
https://doi.org/10.5281/zenodo.14890594

Medicines called antibiotics are used to treat or stop bacterial infections. They have the ability to either eradicate or stop the growth of germs. This historical review's objective is to present data regarding the development and application of antibiotic formulations across time. Examine the following methods: The study material included pertinent texts and scientific papers on the topic, including those listed in the literature for this investigation. Findings: Antibiotics were initially used more than 2,500 years ago by the ancient Chinese. Chinese people employed moldy soybeans to treat furuncles (pimples), carbuncles, and other related ailments after learning about their medicinal qualities. Scottish pharmacologist and biologist Sir Alexander Fleming worked in the fields of immunology, bacteriology, and chemotherapy. He and Florey and Chain were awarded the 1945 Nobel Prize in Physiology and Medicine for their discovery of the first antibiotic, penicillin, in 1928. Conclusions: The antibiotic gradually became the medication of choice. The advantage of modern therapy is the availability of safe and effective antibiotic compositions





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